TB-500 Explained: Thymosin Beta-4 Research, Pricing, and Supplier Quality
TB-500 is sold as a shorthand for thymosin beta-4, but the two are not the same molecule. Understanding that distinction is the first step to reading vendor claims critically.
5mg
Typical vial
$24
Lowest tracked
$39
Median price
188
Vendors listing
TB-500 is a fragment, not the full protein
Thymosin beta-4 is a 43-amino-acid protein. TB-500 as sold is typically a shorter synthetic fragment of the actin-binding region. Vendors frequently use the names interchangeably, which makes like-for-like comparison harder than it should be.
Ask which sequence a listing actually contains. A supplier that cannot answer that question is not a supplier worth its certificate.
The research picture
Around 74 studies in our index reference the compound, concentrated in preclinical wound healing, corneal repair, and cardiac remodelling after induced injury.
Human work exists mainly in ophthalmic formulations rather than systemic injection. We grade the evidence as Emerging: a genuine mechanistic story, very little controlled human outcome data.
Pricing and vial sizes
5mg vials run roughly £19 to £31 across tracked vendors. TB-500 sits slightly above BPC-157 on price, largely because synthesis of the longer sequence costs more.
Watch for listings that quote a 10mg price against a 5mg vial. Our price table normalises everything to price per milligram for exactly this reason.
What to check before ordering
Confirm the stated sequence, look for a batch-matched HPLC trace, and check the mass spectrometry result matches the expected molecular weight of the sequence claimed.
Reconstitution and storage guidance on the product page is a decent secondary signal — vendors who understand handling usually understand testing.
Frequently asked
Is TB-500 the same as thymosin beta-4?
No. TB-500 is generally a synthetic fragment of the larger thymosin beta-4 protein, although many vendors market them under one name.
Why is human data so limited?
Most funded work has focused on topical and ophthalmic applications. Systemic research has stayed largely preclinical.
Search focus for this profile
tb-500 — 12,100/mo searches, difficulty 35/100 — possible. Source: Semrush (UK database).
Supporting terms covered: tb 500 review, tb-500 vs bpc 157, thymosin beta-4 research.
Everything below describes published research and market data. Nothing here is medical advice, and none of these compounds are sold or supplied by CheckALab.