MOTS-c: Research Summary and How to Judge a Supplier
Mitochondrial-derived peptide studied in exercise metabolism and insulin sensitivity models. This profile sets out what is actually published, what a 10mg vial should cost, and the specific documentation to ask for before ordering MOTS-c from any research supplier.
10mg
Typical vial
$25
Lowest tracked
$35
Median price
41
Vendors listing
What MOTS-c is
MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA, studied for AMPK-related metabolic signalling, insulin sensitivity and exercise capacity in rodent models, with human association data linking variants to longevity in some cohorts.
It is one of the better-supported of the mitochondrial-derived peptides, though still without controlled human intervention data.
What the evidence base looks like
The published record is early: a coherent mechanism, a handful of encouraging studies, and very little independent replication at human scale.
Our library records roughly 63 relevant publications for MOTS-c and grades the evidence as emerging. That grade describes the weight of research, not a judgement about safety or effect, and it is reviewed as new work is published.
Supplier quality: what to check on MOTS-c
Methionine oxidation degrades this sequence in storage, and oxidised material can still report high purity.
The practical checklist is the same on every product but weighted differently here: a batch-matched certificate of analysis, an identity method appropriate to this molecule rather than purity alone, clear peptide content per 10mg vial, and a supplier that will answer a technical question before taking payment.
Typical UK pricing
The lowest price we currently track for a 10mg vial is £24.95, against a market median nearer £35. Compare on price per milligram rather than per vial, because vial sizes across suppliers are rarely identical.
A listing well below the tracked low is worth investigating rather than celebrating. On this compound the cost of doing it properly is largely analytical, and that is the first thing an unusually cheap supplier stops paying for.
Frequently asked
Is MOTS-c approved for human use?
No. Everything listed here is supplied for laboratory research use only, and nothing on this page is medical advice.
How much should MOTS-c cost?
Tracked UK prices start around £24.95 for a 10mg vial, with the market median closer to £35.
What is the single most useful check on MOTS-c?
Methionine oxidation degrades this sequence in storage, and oxidised material can still report high purity.
Search focus for this profile
mots-c — Tracked monthly searches, difficulty Monitored. Source: Semrush (UK database).
Supporting terms covered: mots-c review, buy mots-c uk, mots-c price, best mots-c supplier.
Everything below describes published research and market data. Nothing here is medical advice, and none of these compounds are sold or supplied by CheckALab.
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