FOXO4-DRI: Research Summary and How to Judge a Supplier
Senolytic peptide studied for selectively clearing senescent cells in animal models. This profile sets out what is actually published, what a 10mg vial should cost, and the specific documentation to ask for before ordering FOXO4-DRI from any research supplier.
10mg
Typical vial
$170
Lowest tracked
$241
Median price
67
Vendors listing
What FOXO4-DRI is
FOXO4-DRI is a retro-inverso peptide designed to disrupt the FOXO4-p53 interaction that keeps senescent cells alive. The original 2017 work reported clearance of senescent cells and restored fitness markers in aged mice, and it remains one of the most cited single results in senolytics.
Independent replication is thinner than the citation count suggests, and the retro-inverso D-amino-acid construction makes it expensive and technically demanding to synthesise correctly.
What the evidence base looks like
The published record is early: a coherent mechanism, a handful of encouraging studies, and very little independent replication at human scale.
Our library records roughly 13 relevant publications for FOXO4-DRI and grades the evidence as emerging. That grade describes the weight of research, not a judgement about safety or effect, and it is reviewed as new work is published.
Supplier quality: what to check on FOXO4-DRI
The retro-inverso D-amino-acid sequence is the whole point of the molecule, and a standard purity report will not confirm chirality.
The practical checklist is the same on every product but weighted differently here: a batch-matched certificate of analysis, an identity method appropriate to this molecule rather than purity alone, clear peptide content per 10mg vial, and a supplier that will answer a technical question before taking payment.
Typical UK pricing
The lowest price we currently track for a 10mg vial is £169.90, against a market median nearer £241. Compare on price per milligram rather than per vial, because vial sizes across suppliers are rarely identical.
A listing well below the tracked low is worth investigating rather than celebrating. On this compound the cost of doing it properly is largely analytical, and that is the first thing an unusually cheap supplier stops paying for.
Frequently asked
Is FOXO4-DRI approved for human use?
No. Everything listed here is supplied for laboratory research use only, and nothing on this page is medical advice.
How much should FOXO4-DRI cost?
Tracked UK prices start around £169.90 for a 10mg vial, with the market median closer to £241.
What is the single most useful check on FOXO4-DRI?
The retro-inverso D-amino-acid sequence is the whole point of the molecule, and a standard purity report will not confirm chirality.
Search focus for this profile
foxo4-dri — Tracked monthly searches, difficulty Monitored. Source: Semrush (UK database).
Supporting terms covered: foxo4-dri review, buy foxo4-dri uk, foxo4-dri price, best foxo4-dri supplier.
Everything below describes published research and market data. Nothing here is medical advice, and none of these compounds are sold or supplied by CheckALab.
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